119 destinations have scheduled flights from LYS, about 1,181 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| Bordeaux–Mérignac Airport (BOD) | 48 | Easyjet Airline Company Limited, Air France | — |
| Nantes Atlantique Airport (NTE) | 45 | Easyjet Airline Company Limited, Air France | — |
| Charles de Gaulle International Airport (CDG) | 39 | Air France | — |
| Toulouse-Blagnac Airport (TLS) | 39 | Air France, Easyjet Airline Company Limited, AirAsia Japan Co. Ltd., Arax Airlines | — |
| Houari Boumediene Airport (ALG) | 33 | Air Algerie, President Airlines, SETE Linhas Aereas | — |
| Tunis Carthage International Airport (TUN) | 30 | President Airlines, Tunisair, Nouvelair | — |
| Amsterdam Airport Schiphol (AMS) | 28 | KLM | — |
| Frankfurt Main Airport (FRA) | 28 | Lufthansa Cargo, AIR DOLOMITI S.p.A. LINEE AEREE REGIONALI EUROPEE, Yute Air Alaska | — |
| Adolfo Suárez Madrid–Barajas Airport (MAD) | 26 | Iberia, Volotea, Easyjet Airline Company Limited | — |
| Marrakesh Menara Airport (RAK) | 26 | Easyjet Airline Company Limited, President Airlines, Volotea, Royal Air Maroc | — |
| Lisbon Humberto Delgado Airport (LIS) | 24 | TAP Portugal, Easyjet Airline Company Limited | — |
| Francisco de Sá Carneiro Airport (OPO) | 24 | Easyjet Airline Company Limited, President Airlines | — |
| Palma de Mallorca Airport (PMI) | 23 | Easyjet Airline Company Limited, Volotea, President Airlines | — |
| Munich Airport (MUC) | 22 | Lufthansa Cargo, Eagle Air | — |
| Mohammed V International Airport (CMN) | 19 | Royal Air Maroc, Air Arabia Maroc | — |
| Oran Es-Sénia (Ahmed Ben Bella) International Airport (ORN) | 19 | President Airlines, Air Algerie | — |
| İstanbul Airport (IST) | 18 | THY - Turkish Airlines, President Airlines | — |
| London Gatwick Airport (LGW) | 18 | Easyjet Airline Company Limited | — |
| London Heathrow Airport (LHR) | 18 | British Airways | — |
| Athens Eleftherios Venizelos International Airport (ATH) | 17 | Easyjet Airline Company Limited, Aegean Airlines, Volotea, Sky Express S.A., President Airlines | — |
| Josep Tarradellas Barcelona-El Prat Airport (BCN) | 17 | Vueling | — |
| Biarritz Pays Basque airport (BIQ) | 17 | Air France, Easyjet Airline Company Limited | — |
| Djerba Zarzis International Airport (DJE) | 15 | President Airlines, Tunisair, Nouvelair | — |
| Rome–Fiumicino Leonardo da Vinci International Airport (FCO) | 15 | Easyjet Airline Company Limited | — |
| Heraklion International Nikos Kazantzakis Airport (HER) | 14 | President Airlines, Easyjet Airline Company Limited, Volotea, Sky Express S.A. | — |
| Monastir Habib Bourguiba International Airport (MIR) | 14 | President Airlines, Nouvelair, Tunisair | — |
| Brest Bretagne airport (BES) | 13 | Air France, HOP! | — |
| Brussels Airport (BRU) | 13 | Brussels Airlines | — |
| Montreal / Pierre Elliott Trudeau International Airport (YUL) | 13 | Air Benin, Air Canada | — |
| Ajaccio Napoléon Bonaparte airport (AJA) | 12 | Aerotal, Easyjet Airline Company Limited, President Airlines | — |
| Dublin Airport (DUB) | 12 | Aer Lingus | — |
| Ain Arnat Airport (QSF) | 12 | Air Algerie, Volotea | — |
| Venice Marco Polo Airport (VCE) | 12 | Volotea, Easyjet Airline Company Limited | — |
| Bastia-Poretta International airport (BIA) | 11 | Easyjet Airline Company Limited, Aerotal | — |
| Faro - Gago Coutinho International Airport (FAO) | 11 | Easyjet Airline Company Limited, President Airlines, Volotea | — |
| Marseille Provence Airport (MRS) | 11 | Air France | — |
| Caen Carpiquet airport (CFR) | 10 | Air France | — |
| Leipzig/Halle Airport (LEJ) | 10 | Arax Airlines, SATA Air Acores | — |
| Limoges Airport (LIG) | 10 | Air City | — |
| London Luton Airport (LTN) | 10 | Easyjet Airline Company Limited, Air Bagan Ltd. | — |
| Menorca Airport (MAH) | 10 | Easyjet Airline Company Limited, Volotea | — |
| Nice-Côte d'Azur Airport (NCE) | 10 | Air France | — |
| Falcone–Borsellino Airport (PMO) | 10 | Easyjet Airline Company Limited, President Airlines, Volotea | — |
| Pau Pyrénées Airport (PUF) | 10 | Aircompany Trans Asian Airlines | — |
| Rennes-Saint-Jacques Airport (RNS) | 10 | Air France | — |
| Istanbul Sabiha Gökçen International Airport (SAW) | 10 | Pegasus Airlines, Valuair | — |
| Vienna International Airport (VIE) | 10 | Austrian | — |
| Al Massira Airport (AGA) | 9 | President Airlines, Easyjet Airline Company Limited | — |
| Málaga-Costa del Sol Airport (AGP) | 9 | Volotea, President Airlines, Easyjet Airline Company Limited | — |
| Soummam–Abane Ramdane Airport (BJA) | 9 | President Airlines, Air Algerie | — |
| Bari Karol Wojtyła International Airport (BRI) | 9 | Easyjet Airline Company Limited, Volotea | — |
| Mohamed Boudiaf International Airport (CZL) | 9 | Air Algerie, President Airlines | — |
| Figari Sud-Corse Airport (FSC) | 9 | Easyjet Airline Company Limited, Volotea, Aerotal | — |
| Olbia Costa Smeralda Airport (OLB) | 9 | Easyjet Airline Company Limited, Volotea | — |
| Tangier Ibn Battuta Airport (TNG) | 9 | Easyjet Airline Company Limited, Air Arabia Maroc | — |
| Fes Saïss International Airport (FEZ) | 8 | Air Arabia Maroc, President Airlines | — |
| Milan Malpensa International Airport (MXP) | 8 | Aircompany Trans Asian Airlines | — |
| Split Saint Jerome Airport (SPU) | 8 | Easyjet Airline Company Limited, Croatia Airlines, Volotea | — |
| Calvi Sainte Catherine Airport (CLY) | 7 | Easyjet Airline Company Limited, Aerotal, Air France | — |
| Dubai International Airport (DXB) | 7 | Emirates | — |
| Rabat-Salé Airport (RBA) | 7 | Easyjet Airline Company Limited | — |
| Strasbourg Airport (SXB) | 7 | Aircompany Trans Asian Airlines | — |
| Tirana International Airport Mother Teresa (TIA) | 7 | LC Busre SAC, President Airlines | — |
| César Manrique-Lanzarote Airport (ACE) | 6 | Easyjet Airline Company Limited, Volotea | — |
| Copenhagen Kastrup Airport (CPH) | 6 | SAS | — |
| Blaise Diagne International Airport (DSS) | 6 | President Airlines | — |
| Düsseldorf Airport (DUS) | 6 | East-West Airlines | — |
| Kraków John Paul II International Airport (KRK) | 6 | Wizz Air Hungary Ltd. | — |
| Bucharest Henri Coandă International Airport (OTP) | 6 | LC Busre SAC | — |
| Václav Havel Airport Prague (PRG) | 6 | Easyjet Airline Company Limited, Volotea | — |
| Seville Airport (SVQ) | 6 | President Airlines, Easyjet Airline Company Limited | — |
| Warsaw Chopin Airport (WAW) | 6 | LOT Polish Airlines | — |
| Annaba Rabah Bitat Airport (AAE) | 5 | Air Algerie | — |
| Cologne Bonn Airport (CGN) | 5 | AirAsia Japan Co. Ltd. | — |
| Hurghada International Airport (HRG) | 5 | President Airlines, Easyjet Airline Company Limited | — |
| Malta International Airport (MLA) | 5 | Air Malta | — |
| Naples International Airport (NAP) | 5 | Easyjet Airline Company Limited | — |
| Tenerife Sur Airport (TFS) | 5 | Easyjet Airline Company Limited | — |
| Alicante-Elche Miguel Hernández Airport (ALC) | 4 | Easyjet Airline Company Limited, Volotea | — |
| Berlin Brandenburg Airport (BER) | 4 | Easyjet Airline Company Limited | — |
| Chania International Airport (CHQ) | 4 | President Airlines, Easyjet Airline Company Limited | — |
| Dubrovnik Ruđer Bošković Airport (DBV) | 4 | Easyjet Airline Company Limited | — |
| Cristiano Ronaldo International Airport (FNC) | 4 | Easyjet Airline Company Limited, President Airlines | — |
| Zenata – Messali El Hadj Airport (TLM) | 4 | Air Algerie, President Airlines | — |
| Ben Gurion International Airport (TLV) | 4 | EL AL, President Airlines | — |
| Stockholm-Arlanda Airport (ARN) | 3 | Norwegian Air Shuttle A.S. | — |
| Corfu Ioannis Kapodistrias International Airport (CFU) | 3 | Easyjet Airline Company Limited, Volotea | — |
| Catania-Fontanarossa Airport (CTA) | 3 | Easyjet Airline Company Limited | — |
| Edinburgh Airport (EDI) | 3 | Easyjet Airline Company Limited | — |
| Essaouira-Mogador Airport (ESU) | 3 | Easyjet Airline Company Limited | — |
| Florence Airport, Peretola (FLR) | 3 | Volotea | — |
| Geneva International Airport (GVA) | 3 | Ethiopian Airlines | — |
| Ibiza Airport (IBZ) | 3 | Easyjet Airline Company Limited | — |
| Santorini International Airport (JTR) | 3 | President Airlines | — |
| La Rochelle Île de Ré Airport (LRH) | 3 | Easyjet Airline Company Limited | — |
| Oujda Angads Airport (OUD) | 3 | President Airlines | — |
| Alghero-Fertilia Airport (AHO) | 2 | Volotea | — |
| Queen Alia International Airport (AMM) | 2 | Royal Jordanian | — |
| Brindisi Airport (BDS) | 2 | Easyjet Airline Company Limited | — |
| Batna Mostefa Ben Boulaid Airport (BLJ) | 2 | Air Algerie | — |
| Budapest Liszt Ferenc International Airport (BUD) | 2 | Easyjet Airline Company Limited | — |
| Cagliari Elmas Airport (CAG) | 2 | Easyjet Airline Company Limited | — |
| Cairo International Airport (CAI) | 2 | President Airlines | — |
| Mykonos Island National Airport (JMK) | 2 | President Airlines | — |
| David the Builder Kutaisi International Airport (KUT) | 2 | Wizz Air Hungary Ltd. | — |
| Manchester Airport (MAN) | 2 | Easyjet Airline Company Limited | — |
| Oslo-Gardermoen International Airport (OSL) | 2 | Norwegian Air Shuttle A.S. | — |
| Poitiers-Biard Airport (PIS) | 2 | Volotea | — |
| Priština Adem Jashari International Airport (PRN) | 2 | Easyjet Airline Company Limited | — |
| Salerno Costa d'Amalfi Airport (QSR) | 2 | Volotea | — |
| Rhodes International Airport "Diagoras" (RHO) | 2 | President Airlines, Volotea | — |
| Valencia Airport (VLC) | 2 | Volotea | — |
| Antalya International Airport (AYT) | 1 | President Airlines | — |
| Beirut Rafic Hariri International Airport (BEY) | 1 | President Airlines | — |
| Bologna Guglielmo Marconi Airport (BLQ) | 1 | Aircompany Trans Asian Airlines | — |
| Biskra - Mohamed Khider Airport (BSK) | 1 | Air Algerie | — |
| Zvartnots International Airport (EVN) | 1 | President Airlines | — |
| Luxor International Airport (LXR) | 1 | Air Cairo | — |
| Sharm El Sheikh International Airport (SSH) | 1 | Easyjet Airline Company Limited | — |
GET /routes returns each scheduled flight from LYS: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
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