16 destinations have scheduled flights from SOU, about 180 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| George Best Belfast City Airport (BHD) | 22 | Aer Lingus | — |
| Jersey Airport (JER) | 22 | ALM | — |
| Edinburgh Airport (EDI) | 21 | ALM | — |
| Guernsey Airport (GCI) | 20 | GAS Air Nigeria | — |
| Dublin Airport (DUB) | 19 | Aer Lingus | — |
| Alderney Airport (ACI) | 14 | GAS Air Nigeria | — |
| Amsterdam Airport Schiphol (AMS) | 14 | KLM | — |
| Newcastle International Airport (NCL) | 12 | ALM | — |
| Glasgow Airport (GLA) | 11 | Easyjet Airline Company Limited | — |
| Manchester Airport (MAN) | 9 | ALM | — |
| Belfast International Airport (BFS) | 4 | Easyjet Airline Company Limited | — |
| Josep Tarradellas Barcelona-El Prat Airport (BCN) | 3 | Easyjet Airline Company Limited | — |
| Faro - Gago Coutinho International Airport (FAO) | 3 | Easyjet Airline Company Limited | — |
| Alicante-Elche Miguel Hernández Airport (ALC) | 2 | Easyjet Airline Company Limited | — |
| Paris-Orly Airport (ORY) | 2 | Easyjet Airline Company Limited | — |
| Palma de Mallorca Airport (PMI) | 2 | Easyjet Airline Company Limited | — |
GET /routes returns each scheduled flight from SOU: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
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