78 destinations have scheduled flights from MDW, about 1,914 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| Hartsfield-jackson Atlanta International (ATL) | 75 | Southwest Airlines Co., Delta Air Lines, Frontier Airlines, Inc. | — |
| Phoenix (PHX) | 73 | Southwest Airlines Co., Frontier Airlines, Inc. | — |
| Orlando International (MCO) | 68 | Southwest Airlines Co., Frontier Airlines, Inc. | — |
| Detroit Metropolitan Wayne County (DTW) | 63 | Delta Air Lines, Southwest Airlines Co. | — |
| New York (LGA) | 63 | Southwest Airlines Co. | — |
| Ronald Reagan Washington National Airport (DCA) | 59 | Southwest Airlines Co. | — |
| Minneapolis - St. Paul International (MSP) | 59 | Southwest Airlines Co., Delta Air Lines | — |
| Denver International (DEN) | 58 | Southwest Airlines Co. | — |
| Kansas City International Airport (MCI) | 55 | Southwest Airlines Co. | — |
| Nashville International (BNA) | 50 | Southwest Airlines Co. | — |
| Love Field (DAL) | 48 | Southwest Airlines Co. | — |
| Las Vegas (LAS) | 48 | Southwest Airlines Co. | — |
| William P Hobby (HOU) | 46 | Southwest Airlines Co. | — |
| Tampa International (TPA) | 46 | Southwest Airlines Co. | — |
| Philadelphia International (PHL) | 41 | Southwest Airlines Co. | — |
| Fort Myers (RSW) | 41 | Southwest Airlines Co. | — |
| Logan International (BOS) | 39 | Southwest Airlines Co. | — |
| Omaha (OMA) | 36 | Southwest Airlines Co. | — |
| Lambert-St. Louis International (STL) | 36 | Southwest Airlines Co. | — |
| Pittsburgh International (PIT) | 35 | Southwest Airlines Co. | — |
| Hopkins International (CLE) | 34 | Southwest Airlines Co. | — |
| Port Columbus International (CMH) | 34 | Southwest Airlines Co. | — |
| Austin-bergstrom International (AUS) | 32 | Southwest Airlines Co. | — |
| Baltimore/Washington International Thurgood Marshall (BWI) | 32 | Southwest Airlines Co. | — |
| Fort Lauderdale–Hollywood International (FLL) | 32 | Southwest Airlines Co. | — |
| Albany International (ALB) | 30 | Southwest Airlines Co. | — |
| Cincinnati/Northern Kentucky (CVG) | 29 | Southwest Airlines Co. | — |
| Rochester (ROC) | 29 | Southwest Airlines Co. | — |
| Los Angeles International (LAX) | 28 | Southwest Airlines Co. | — |
| Gerald R. Ford International (GRR) | 27 | Southwest Airlines Co. | — |
| Louisville International (Standiford Field) (SDF) | 27 | Southwest Airlines Co. | — |
| Louis Armstrong New Orléans International Airport (MSY) | 26 | Southwest Airlines Co. | — |
| Buffalo Niagara International (BUF) | 25 | Southwest Airlines Co. | — |
| Providence (PVD) | 24 | Southwest Airlines Co. | — |
| Charlotte Douglas (CLT) | 23 | Southwest Airlines Co. | — |
| Bradley International (BDL) | 22 | Southwest Airlines Co. | — |
| Raleigh-durham International Airport (RDU) | 21 | Southwest Airlines Co. | — |
| San Diego (SAN) | 21 | Southwest Airlines Co. | — |
| Manchester-boston Regional Airport (MHT) | 19 | Southwest Airlines Co. | — |
| Indianapolis International (IND) | 18 | Southwest Airlines Co. | — |
| Jacksonville, (JAX) | 18 | Southwest Airlines Co. | — |
| Sarasota/Bradenton International (SRQ) | 18 | Southwest Airlines Co. | — |
| Savannah/Hilton Head (SAV) | 16 | Southwest Airlines Co. | — |
| Miami International Airport (MIA) | 15 | Southwest Airlines Co., Frontier Airlines, Inc. | — |
| Richmond (RIC) | 15 | Southwest Airlines Co. | — |
| Norfolk (ORF) | 14 | Southwest Airlines Co. | — |
| Sacramento (SMF) | 14 | Southwest Airlines Co. | — |
| Birmingham (BHM) | 12 | Southwest Airlines Co. | — |
| Charleston, AFB Municipal (CHS) | 12 | Southwest Airlines Co. | — |
| Des Moines (DSM) | 11 | Southwest Airlines Co. | — |
| Memphis (MEM) | 11 | Southwest Airlines Co. | — |
| Will Rogers World Airport (OKC) | 11 | Southwest Airlines Co. | — |
| Seattle-Tacoma International (SEA) | 11 | Southwest Airlines Co. | — |
| San Francisco International (SFO) | 11 | Southwest Airlines Co. | — |
| General Mitchell International (MKE) | 10 | Southwest Airlines Co. | — |
| Francisco J. Múgica Internacional (MLM) | 10 | Volaris | — |
| Portland International (PDX) | 10 | Southwest Airlines Co. | — |
| San Antonio (SAT) | 10 | Southwest Airlines Co. | — |
| Tulsa (TUL) | 10 | Southwest Airlines Co. | — |
| Tucson (TUS) | 10 | Southwest Airlines Co. | — |
| Oakland (OAK) | 9 | Southwest Airlines Co. | — |
| Salt Lake City International (SLC) | 9 | Southwest Airlines Co. | — |
| Mid-Continent (ICT) | 8 | Southwest Airlines Co. | — |
| Albuquerque International (ABQ) | 7 | Southwest Airlines Co. | — |
| Don Miguel Hidalgo y Costilla International (GDL) | 7 | Volaris | — |
| Ontario International (ONT) | 7 | Southwest Airlines Co. | — |
| Aguascalients (AGU) | 6 | Volaris | — |
| Cancún International (CUN) | 5 | Southwest Airlines Co. | — |
| Dallas/Fort Worth International (DFW) | 5 | Frontier Airlines, Inc. | — |
| NW Florida Beaches Int (ECP) | 5 | Southwest Airlines Co. | — |
| San Jose (SJC) | 5 | Southwest Airlines Co. | — |
| Zacatecas City (ZCL) | 4 | Volaris | — |
| Del Bajío International (BJX) | 3 | Volaris | — |
| Bob Hope (BUR) | 3 | Southwest Airlines Co. | — |
| Guadalupe Victoria (DGO) | 3 | Volaris | — |
| Long Beach Municipal (LGB) | 3 | Southwest Airlines Co. | — |
| George Bush Intercontinental (IAH) | 2 | Frontier Airlines, Inc. | — |
| Pensacola (PNS) | 2 | Southwest Airlines Co. | — |
GET /routes returns each scheduled flight from MDW: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
https://www.goflightlabs.com/routes?access_key=YOUR_ACCESS_KEY&dep_iata=MDW
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