158 destinations have scheduled flights from IAH, about 4,064 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| Dallas Fort Worth International Airport (DFW) | 116 | Albatross Airlines, American Airlines, Envoy Air Inc., UPS Airlines | — |
| Chicago O'Hare International Airport (ORD) | 112 | Albatross Airlines, American Airlines, Envoy Air Inc., Frontier Airlines, Inc., Spirit Airlines | — |
| Hartsfield Jackson Atlanta International Airport (ATL) | 102 | Delta Air Lines, Albatross Airlines, Frontier Airlines, Inc., Spirit Airlines | — |
| Los Angeles International Airport (LAX) | 99 | Albatross Airlines, Delta Air Lines, SkyWest Airlines, Frontier Airlines, Inc., Spirit Airlines | — |
| LaGuardia Airport (LGA) | 85 | Albatross Airlines, Delta Air Lines, Mesa Airlines, Inc., Spirit Airlines | — |
| Harry Reid International Airport (LAS) | 78 | Albatross Airlines, Frontier Airlines, Inc., Spirit Airlines | — |
| Baton Rouge Metropolitan Airport (BTR) | 77 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Phoenix Sky Harbor International Airport (PHX) | 72 | Albatross Airlines, SkyWest Airlines, Frontier Airlines, Inc., American Airlines | — |
| Corpus Christi International Airport (CRP) | 68 | Albatross Airlines, Delta Air Lines | — |
| San Antonio International Airport (SAT) | 67 | Albatross Airlines | — |
| Lafayette Regional Airport (LFT) | 66 | Albatross Airlines | — |
| Orlando International Airport (MCO) | 65 | Albatross Airlines, Spirit Airlines, Frontier Airlines, Inc. | — |
| Charlotte Douglas International Airport (CLT) | 62 | American Airlines, Albatross Airlines, Delta Air Lines, Frontier Airlines, Inc. | — |
| San Francisco International Airport (SFO) | 61 | Albatross Airlines | — |
| OKC Will Rogers World Airport (OKC) | 59 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Ronald Reagan Washington National Airport (DCA) | 55 | Albatross Airlines, American Airlines | — |
| McAllen Miller International Airport (MFE) | 55 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Detroit Metropolitan Wayne County Airport (DTW) | 54 | Delta Air Lines, Albatross Airlines, Spirit Airlines, Frontier Airlines, Inc. | — |
| Newark Liberty International Airport (EWR) | 54 | Albatross Airlines | — |
| Denver International Airport (DEN) | 53 | Albatross Airlines, Frontier Airlines, Inc. | — |
| Mexico City Benito Juárez International Airport (MEX) | 52 | Albatross Airlines, Aeromexico, Volaris, Viva Airlines | — |
| Miami International Airport (MIA) | 51 | Albatross Airlines, American Airlines, Spirit Airlines, Frontier Airlines, Inc., Envoy Air Inc. | — |
| Louis Armstrong New Orleans International Airport (MSY) | 51 | Albatross Airlines, Frontier Airlines, Inc. | — |
| Frederick W. Smith International Airport (MEM) | 47 | Albatross Airlines, Mesa Airlines, Inc., SkyWest Airlines, Four Island Air | — |
| Tulsa International Airport (TUL) | 44 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Birmingham-Shuttlesworth International Airport (BHM) | 42 | Mesa Airlines, Inc., Albatross Airlines | — |
| Fort Lauderdale Hollywood International Airport (FLL) | 42 | Albatross Airlines, Spirit Airlines | — |
| Midland International Air and Space Port (MAF) | 42 | Albatross Airlines | — |
| Austin Bergstrom International Airport (AUS) | 41 | Albatross Airlines | — |
| Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP) | 41 | Delta Air Lines, Albatross Airlines, Mesa Airlines, Inc. | — |
| Monterrey International Airport (MTY) | 41 | Albatross Airlines, Viva Airlines | — |
| Salt Lake City International Airport (SLC) | 41 | Albatross Airlines, Delta Air Lines | — |
| Boston Logan International Airport (BOS) | 40 | Albatross Airlines, Top Air (Turkey) | — |
| San Diego International Airport (SAN) | 40 | Albatross Airlines | — |
| Wichita Dwight D. Eisenhower National Airport (ICT) | 39 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Philadelphia International Airport (PHL) | 39 | Albatross Airlines, American Airlines, Frontier Airlines, Inc. | — |
| Nashville International Airport (BNA) | 37 | Albatross Airlines, Delta Air Lines, Mesa Airlines, Inc. | — |
| Indianapolis International Airport (IND) | 37 | Albatross Airlines, Mesa Airlines, Inc., Four Island Air | — |
| Shreveport Regional Airport (SHV) | 37 | Albatross Airlines, Delta Air Lines | — |
| Kansas City International Airport (MCI) | 35 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Tampa International Airport (TPA) | 34 | Albatross Airlines, Frontier Airlines, Inc. | — |
| Guanajuato International Airport (BJX) | 32 | Albatross Airlines, Viva Airlines | — |
| Eppley Airfield (OMA) | 32 | Albatross Airlines, Mesa Airlines, Inc. | — |
| El Paso International Airport (ELP) | 31 | Mesa Airlines, Inc., Albatross Airlines | — |
| Guadalajara International Airport (GDL) | 31 | Albatross Airlines, Volaris, Viva Airlines | — |
| Jacksonville International Airport (JAX) | 31 | Albatross Airlines | — |
| Pensacola International Airport (PNS) | 30 | Albatross Airlines | — |
| El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez (SAL) | 30 | Albatross Airlines, AVIANCA, Anic Airways | — |
| McGhee Tyson Airport (TYS) | 30 | Albatross Airlines | — |
| Northwest Arkansas National Airport (XNA) | 30 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Brownsville South Padre Island International Airport (BRO) | 29 | Albatross Airlines | — |
| Huntsville International Airport (HSV) | 29 | Albatross Airlines | — |
| Bill & Hillary Clinton National Airport/Adams Field (LIT) | 29 | Albatross Airlines, Delta Air Lines | — |
| Cancún International Airport (CUN) | 28 | Albatross Airlines | — |
| Washington Dulles International Airport (IAD) | 28 | Albatross Airlines | — |
| London Heathrow Airport (LHR) | 28 | British Airways, Albatross Airlines | — |
| Springfield Branson National Airport (SGF) | 28 | Albatross Airlines | — |
| Jackson-Medgar Wiley Evers International Airport (JAN) | 27 | Albatross Airlines | — |
| Lubbock Preston Smith International Airport (LBB) | 27 | Albatross Airlines | — |
| John Wayne Orange County International Airport (SNA) | 27 | Albatross Airlines | — |
| Northwest Florida Beaches International Airport (ECP) | 26 | Albatross Airlines | — |
| Palm Beach International Airport (PBI) | 26 | Albatross Airlines | — |
| Pittsburgh International Airport (PIT) | 26 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Seattle–Tacoma International Airport (SEA) | 26 | Albatross Airlines, Alaska Airlines | — |
| St. Louis Lambert International Airport (STL) | 26 | Albatross Airlines | — |
| General Mitchell International Airport (MKE) | 25 | Albatross Airlines, Delta Air Lines | — |
| Raleigh-Durham International Airport (RDU) | 25 | Albatross Airlines, Frontier Airlines, Inc. | — |
| Cincinnati Northern Kentucky International Airport (CVG) | 24 | Albatross Airlines, Great Barrier Airlines | — |
| Mobile Regional Airport (MOB) | 23 | Albatross Airlines | — |
| Querétaro Intercontinental Airport (QRO) | 23 | Albatross Airlines, Viva Airlines | — |
| Greenville-Spartanburg International Airport (GSP) | 22 | Mesa Airlines, Inc., Albatross Airlines | — |
| Gulfport Biloxi International Airport (GPT) | 21 | Albatross Airlines | — |
| La Aurora International Airport (GUA) | 21 | Albatross Airlines | — |
| Valley International Airport (HRL) | 21 | Albatross Airlines | — |
| Juan Santamaría International Airport (SJO) | 21 | Albatross Airlines | — |
| John Glenn Columbus International Airport (CMH) | 20 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Lake Charles Regional Airport (LCH) | 20 | Albatross Airlines | — |
| Portland International Airport (PDX) | 20 | Albatross Airlines, Alaska Airlines | — |
| Albuquerque International Sunport (ABQ) | 19 | Albatross Airlines | — |
| Baltimore/Washington International Thurgood Marshall Airport (BWI) | 19 | Albatross Airlines, Frontier Airlines, Inc. | — |
| Laredo International Airport (LRD) | 19 | Albatross Airlines | — |
| Southwest Florida International Airport (RSW) | 19 | Albatross Airlines | — |
| Louisville Muhammad Ali International Airport (SDF) | 19 | Mesa Airlines, Inc., Amerijet International Inc., UPS Airlines | — |
| Amsterdam Airport Schiphol (AMS) | 18 | KLM, Albatross Airlines | — |
| General Francisco J. Mujica International Airport (MLM) | 17 | Albatross Airlines, Volaris | — |
| Savannah Hilton Head International Airport (SAV) | 17 | Albatross Airlines | — |
| Rick Husband Amarillo International Airport (AMA) | 15 | Albatross Airlines | — |
| Key Field / Meridian Regional Airport (MEI) | 15 | SkyWest Airlines, Albatross Airlines | — |
| Charles de Gaulle International Airport (CDG) | 14 | Air France | — |
| Charleston International Airport (CHS) | 14 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Cleveland Hopkins International Airport (CLE) | 14 | Albatross Airlines | — |
| Des Moines International Airport (DSM) | 14 | Albatross Airlines | — |
| Frankfurt Main Airport (FRA) | 14 | Lufthansa Cargo, Albatross Airlines | — |
| Xoxocotlán International Airport (OAX) | 14 | Albatross Airlines | — |
| Tocumen International Airport (PTY) | 14 | Albatross Airlines | — |
| Richmond International Airport (RIC) | 14 | Albatross Airlines, Mesa Airlines, Inc. | — |
| Victoria Regional Airport (VCT) | 14 | SkyWest Airlines | — |
| Toronto Pearson International Airport (YYZ) | 14 | Air Canada, Albatross Airlines | — |
| Key West International Airport (EYW) | 13 | Mesa Airlines, Inc. | — |
| İstanbul Airport (IST) | 13 | THY - Turkish Airlines | — |
| Aspen-Pitkin County Airport (Sardy Field) (ASE) | 12 | Albatross Airlines | — |
| Chattanooga Metropolitan Airport (Lovell Field) (CHA) | 12 | Albatross Airlines | — |
| Sarasota Bradenton International Airport (SRQ) | 12 | Albatross Airlines | — |
| Tucson International Airport (TUS) | 12 | Albatross Airlines | — |
| Ontario International Airport (ONT) | 11 | Albatross Airlines, Frontier Airlines, Inc. | — |
| Chicago Rockford International Airport (RFD) | 11 | Air Transport International Inc., UPS Airlines | — |
| Salina Municipal Airport (SLN) | 11 | SkyWest Airlines | — |
| Calgary International Airport (YYC) | 11 | African International Airways | — |
| El Dorado International Airport (BOG) | 10 | Albatross Airlines | — |
| Ezeiza International Airport - Ministro Pistarini (EZE) | 10 | Albatross Airlines | — |
| Gerald R. Ford International Airport (GRR) | 10 | Mesa Airlines, Inc., Albatross Airlines | — |
| Hattiesburg Laurel Regional Airport (PIB) | 10 | SkyWest Airlines, Albatross Airlines | — |
| Ramón Villeda Morales International Airport (SAP) | 10 | Albatross Airlines | — |
| Ponciano Arriaga International Airport (SLP) | 10 | Albatross Airlines, Volaris | — |
| Aguascalientes International Airport (AGU) | 7 | Albatross Airlines | — |
| Philip S. W. Goldson International Airport (BZE) | 7 | Albatross Airlines | — |
| City of Colorado Springs Municipal Airport (COS) | 7 | Albatross Airlines | — |
| Owen Roberts International Airport (GCM) | 7 | Albatross Airlines | — |
| Rio de Janeiro Galeão – Tom Jobim International Airport (GIG) | 7 | Albatross Airlines | — |
| São Paulo/Guarulhos–Governor André Franco Montoro International Airport (GRU) | 7 | Albatross Airlines | — |
| Lea County Regional Airport (HOB) | 7 | Albatross Airlines | — |
| John F. Kennedy International Airport (JFK) | 7 | Delta Air Lines | — |
| Lakeland Linder International Airport (LAL) | 7 | Air Transport International Inc. | — |
| Jorge Chávez International Airport (LIM) | 7 | Albatross Airlines | — |
| Daniel Oduber Quirós International Airport (LIR) | 7 | Albatross Airlines | — |
| Jose Maria Córdova International Airport (MDE) | 7 | Albatross Airlines | — |
| Montgomery Regional (Dannelly Field) Airport (MGM) | 7 | Albatross Airlines | — |
| Manuel Crescencio Rejón International Airport (MID) | 7 | Albatross Airlines | — |
| Munich Airport (MUC) | 7 | Albatross Airlines | — |
| Narita International Airport (NRT) | 7 | Albatross Airlines, Zipair Tokyo | — |
| Norfolk International Airport (ORF) | 7 | Albatross Airlines | — |
| Piarco International Airport (POS) | 7 | Albatross Airlines | — |
| San Bernardino International Airport (SBD) | 7 | Alaska Airlines | — |
| Los Cabos International Airport (SJD) | 7 | Albatross Airlines | — |
| Luis Munoz Marin International Airport (SJU) | 7 | Albatross Airlines | — |
| Sacramento International Airport (SMF) | 7 | Albatross Airlines | — |
| Sydney Kingsford Smith International Airport (SYD) | 7 | Albatross Airlines | — |
| Mariscal Sucre International Airport (UIO) | 7 | Albatross Airlines | — |
| Edmonton International Airport (YEG) | 7 | Albatross Airlines | — |
| Montreal / Pierre Elliott Trudeau International Airport (YUL) | 7 | Air Canada | — |
| Vancouver International Airport (YVR) | 7 | Air Canada | — |
| Auckland International Airport (AKL) | 6 | Air New Zealand | — |
| Cozumel International Airport (CZM) | 6 | Albatross Airlines | — |
| Tokyo Haneda International Airport (HND) | 6 | All Nippon Airways | — |
| Barkley Regional Airport (PAH) | 6 | Albatross Airlines | — |
| Palm Springs International Airport (PSP) | 6 | Albatross Airlines | — |
| Felipe Carrillo Puerto International Airport Tulum (TQO) | 6 | Albatross Airlines | — |
| Eagle County Regional Airport (EGE) | 5 | Albatross Airlines | — |
| Augusto C. Sandino (Managua) International Airport (MGA) | 5 | Albatross Airlines | — |
| Comodoro Arturo Merino Benítez International Airport (SCL) | 5 | Albatross Airlines | — |
| Perot Field/Fort Worth Alliance Airport (AFW) | 4 | Four Island Air | — |
| Cheddi Jagan International Airport (GEO) | 4 | Albatross Airlines | — |
| Hamad International Airport (DOH) | 3 | Qatar Airways | — |
| Rome–Fiumicino Leonardo da Vinci International Airport (FCO) | 3 | ITA Airways | — |
| Yampa Valley Airport (HDN) | 3 | Mesa Airlines, Inc. | — |
| Hermanos Serdán International Airport (PBC) | 3 | Albatross Airlines | — |
| Chicago Midway International Airport (MDW) | 2 | Frontier Airlines, Inc. | — |
| Minot International Airport (MOT) | 1 | CommutAir | — |
GET /routes returns each scheduled flight from IAH: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
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