20 destinations have scheduled flights from PNS, about 258 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| Hartsfield Jackson Atlanta International Airport (ATL) | 36 | Delta Air Lines | — |
| Dallas Fort Worth International Airport (DFW) | 31 | American Airlines, Envoy Air Inc. | — |
| Charlotte Douglas International Airport (CLT) | 27 | American Airlines, Envoy Air Inc. | — |
| Miami International Airport (MIA) | 25 | Envoy Air Inc., UPS Airlines, American Airlines | — |
| Chicago O'Hare International Airport (ORD) | 22 | Albatross Airlines, Envoy Air Inc. | — |
| Ronald Reagan Washington National Airport (DCA) | 19 | American Airlines | — |
| Denver International Airport (DEN) | 19 | Albatross Airlines, Southwest Airlines Co., Frontier Airlines, Inc. | — |
| Nashville International Airport (BNA) | 13 | Southwest Airlines Co. | — |
| LaGuardia Airport (LGA) | 13 | Delta Air Lines | — |
| Orlando International Airport (MCO) | 8 | Spirit Airlines, Frontier Airlines, Inc. | — |
| Fort Lauderdale Hollywood International Airport (FLL) | 7 | Spirit Airlines | — |
| George Bush Intercontinental Airport (IAH) | 7 | Albatross Airlines | — |
| Chicago Midway International Airport (MDW) | 5 | Southwest Airlines Co. | — |
| Louisville Muhammad Ali International Airport (SDF) | 5 | UPS Airlines | — |
| St. Louis Lambert International Airport (STL) | 5 | Southwest Airlines Co. | — |
| Tampa International Airport (TPA) | 5 | Mexicana | — |
| Kansas City International Airport (MCI) | 4 | Southwest Airlines Co. | — |
| Austin Bergstrom International Airport (AUS) | 3 | Southwest Airlines Co. | — |
| Southwest Georgia Regional Airport (ABY) | 2 | UPS Airlines | — |
| Frederick W. Smith International Airport (MEM) | 2 | Mexicana | — |
GET /routes returns each scheduled flight from PNS: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
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