73 destinations have scheduled flights from SAN, about 1,969 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| San Francisco International (SFO) | 150 | Alaska Airlines, United Airlines, Southwest Airlines Co., Frontier Airlines, Inc., American Airlines | — |
| Phoenix (PHX) | 129 | Southwest Airlines Co., American Airlines, Alaska Airlines, Frontier Airlines, Inc. | — |
| Las Vegas (LAS) | 125 | Southwest Airlines Co., Alaska Airlines, American Airlines, Frontier Airlines, Inc. | — |
| Sacramento (SMF) | 123 | Southwest Airlines Co., Alaska Airlines, American Airlines, United Airlines | — |
| San Jose (SJC) | 115 | Southwest Airlines Co., Alaska Airlines, United Airlines, American Airlines | — |
| Denver International (DEN) | 98 | Southwest Airlines Co., United Airlines, American Airlines, Frontier Airlines, Inc., Alaska Airlines | — |
| Seattle-Tacoma International (SEA) | 67 | Alaska Airlines, Delta Air Lines | — |
| Oakland (OAK) | 60 | Southwest Airlines Co., Federal Express | — |
| Salt Lake City International (SLC) | 59 | Delta Air Lines, American Airlines, Southwest Airlines Co., Alaska Airlines, Frontier Airlines, Inc. | — |
| Chicago O'hare International (ORD) | 50 | American Airlines, United Airlines, Alaska Airlines | — |
| John F Kennedy International (JFK) | 48 | Delta Air Lines, JetBlue, Alaska Airlines | — |
| Austin-bergstrom International (AUS) | 43 | Southwest Airlines Co., American Airlines, Alaska Airlines, Frontier Airlines, Inc. | — |
| Reno (RNO) | 39 | Alaska Airlines, Southwest Airlines Co., American Airlines | — |
| Honolulu International (HNL) | 36 | Alaska Airlines, Southwest Airlines Co. | — |
| Dallas/Fort Worth International (DFW) | 34 | American Airlines | — |
| Logan International (BOS) | 31 | JetBlue, Delta Air Lines | — |
| Charlotte Douglas (CLT) | 30 | American Airlines | — |
| Fresno Air Terminal Airport (FAT) | 30 | Alaska Airlines, Southwest Airlines Co., United Airlines | — |
| Monterey (MRY) | 30 | Alaska Airlines, American Airlines | — |
| Minneapolis - St. Paul International (MSP) | 30 | Delta Air Lines, MN Airlines LLC | — |
| Portland International (PDX) | 29 | Alaska Airlines | — |
| Los Angeles International (LAX) | 28 | Delta Air Lines, United Airlines | — |
| Baltimore/Washington International Thurgood Marshall (BWI) | 27 | Southwest Airlines Co. | — |
| Hartsfield-jackson Atlanta International (ATL) | 26 | Delta Air Lines | — |
| Love Field (DAL) | 26 | Southwest Airlines Co. | — |
| Orlando International (MCO) | 24 | Alaska Airlines, Southwest Airlines Co. | — |
| San Luis Obispo (SBP) | 24 | Alaska Airlines, American Airlines | — |
| Boise Air Terminal/Gowen Field (BOI) | 23 | Alaska Airlines, Southwest Airlines Co. | — |
| George Bush Intercontinental (IAH) | 21 | United Airlines | — |
| Santa Rosa (STS) | 21 | Alaska Airlines, American Airlines | — |
| Eugene (EUG) | 20 | Alaska Airlines, American Airlines | — |
| Newark Liberty International (EWR) | 20 | United Airlines | — |
| Miami International Airport (MIA) | 20 | American Airlines | — |
| Washington Dulles International (IAD) | 19 | United Airlines | — |
| Detroit Metropolitan Wayne County (DTW) | 18 | Delta Air Lines | — |
| William P Hobby (HOU) | 18 | Southwest Airlines Co. | — |
| Vancouver International (YVR) | 18 | Air Canada | — |
| Nashville International (BNA) | 17 | Southwest Airlines Co. | — |
| Albuquerque International (ABQ) | 13 | Southwest Airlines Co. | — |
| Everett (PAE) | 13 | Alaska Airlines | — |
| Lester B. Pearson International (YYZ) | 13 | Air Canada | — |
| Midway (MDW) | 12 | Southwest Airlines Co. | — |
| Tucson (TUS) | 12 | Southwest Airlines Co. | — |
| El Paso International Airport (ELP) | 11 | Southwest Airlines Co., Star Up S.A. dba Star Peru | — |
| Roberts Field (RDM) | 11 | Alaska Airlines | — |
| Kansas City International Airport (MCI) | 10 | Southwest Airlines Co. | — |
| San Antonio (SAT) | 10 | Southwest Airlines Co. | — |
| Lambert-St. Louis International (STL) | 10 | Southwest Airlines Co. | — |
| Spokane International (GEG) | 9 | Alaska Airlines | — |
| Indianapolis International (IND) | 8 | Federal Express, Southwest Airlines Co. | — |
| Ronald Reagan Washington National Airport (DCA) | 7 | Alaska Airlines | — |
| Fort Lauderdale–Hollywood International (FLL) | 7 | Alaska Airlines | — |
| Heathrow (LHR) | 7 | British Airways | — |
| Kahului (OGG) | 7 | Alaska Airlines | — |
| Licenciado Gustavo Díaz Ordaz International (PVR) | 7 | Alaska Airlines | — |
| Tampa International (TPA) | 7 | Alaska Airlines | — |
| Kona International Airport (KOA) | 6 | Alaska Airlines | — |
| Philadelphia International (PHL) | 6 | American Airlines | — |
| Colorado Springs (COS) | 5 | Southwest Airlines Co. | — |
| Memphis (MEM) | 5 | Federal Express | — |
| Franz Josef Strauss (MUC) | 5 | Lufthansa Cargo | — |
| Louisville International (Standiford Field) (SDF) | 5 | UPS Airlines | — |
| Port Columbus International (CMH) | 4 | Southwest Airlines Co. | — |
| Eagle County (EGE) | 4 | Alaska Airlines | — |
| Rogue Valley International - Medford Airport (MFR) | 4 | American Airlines | — |
| Narita International Airport (NRT) | 4 | Japan Airlines | — |
| Tocumen International (PTY) | 4 | COPA Airlines | — |
| Calgary (YYC) | 4 | WestJet | — |
| Schiphol (AMS) | 3 | KLM | — |
| General Mitchell International (MKE) | 3 | Southwest Airlines Co. | — |
| Los Cabos (SJD) | 3 | Alaska Airlines | — |
| Gallatin Field (BZN) | 2 | American Airlines | — |
| Ontario International (ONT) | 2 | Federal Express | — |
GET /routes returns each scheduled flight from SAN: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
https://www.goflightlabs.com/routes?access_key=YOUR_ACCESS_KEY&dep_iata=SAN
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