109 destinations have scheduled flights from BOS, about 2,059 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| LaGuardia Airport (LGA) | 95 | Delta Air Lines, American Airlines | — |
| Ronald Reagan Washington National Airport (DCA) | 92 | Delta Air Lines, Top Air (Turkey), American Airlines | — |
| Chicago O'Hare International Airport (ORD) | 88 | American Airlines, Albatross Airlines, Delta Air Lines, Top Air (Turkey) | — |
| Hartsfield Jackson Atlanta International Airport (ATL) | 60 | Delta Air Lines, Top Air (Turkey), Frontier Airlines, Inc. | — |
| John F. Kennedy International Airport (JFK) | 59 | Top Air (Turkey), Delta Air Lines, American Airlines | — |
| Philadelphia International Airport (PHL) | 55 | American Airlines, Delta Air Lines, Top Air (Turkey), UPS Airlines | — |
| Baltimore/Washington International Thurgood Marshall Airport (BWI) | 47 | Southwest Airlines Co., Delta Air Lines, Star Up S.A. dba Star Peru | — |
| Nashville International Airport (BNA) | 43 | Southwest Airlines Co., Top Air (Turkey), Delta Air Lines | — |
| Charlotte Douglas International Airport (CLT) | 41 | American Airlines, Delta Air Lines | — |
| San Francisco International Airport (SFO) | 41 | Albatross Airlines, Top Air (Turkey), Delta Air Lines | — |
| Dallas Fort Worth International Airport (DFW) | 40 | American Airlines, Delta Air Lines | — |
| London Heathrow Airport (LHR) | 40 | British Airways, Intercontinental Airlines, American Airlines, Top Air (Turkey), Delta Air Lines | — |
| Newark Liberty International Airport (EWR) | 38 | Albatross Airlines, Delta Air Lines, Four Island Air | — |
| Los Angeles International Airport (LAX) | 38 | Top Air (Turkey), Delta Air Lines, Albatross Airlines, American Airlines | — |
| Denver International Airport (DEN) | 37 | Albatross Airlines, Southwest Airlines Co., Top Air (Turkey) | — |
| Orlando International Airport (MCO) | 36 | Top Air (Turkey), Delta Air Lines | — |
| Miami International Airport (MIA) | 36 | American Airlines, Delta Air Lines | — |
| Nantucket Memorial Airport (ACK) | 35 | Hyannis Air Service, Inc. d/b/a Cap, Top Air (Turkey) | — |
| Detroit Metropolitan Wayne County Airport (DTW) | 35 | Delta Air Lines, Top Air (Turkey) | — |
| Raleigh-Durham International Airport (RDU) | 35 | Top Air (Turkey), Delta Air Lines, Frontier Airlines, Inc. | — |
| Cincinnati Northern Kentucky International Airport (CVG) | 33 | Delta Air Lines, American Airlines, Envoy Air Inc. | — |
| Dublin Airport (DUB) | 30 | Aer Lingus, Top Air (Turkey), Delta Air Lines | — |
| Indianapolis International Airport (IND) | 29 | American Airlines, Delta Air Lines, Four Island Air | — |
| Austin Bergstrom International Airport (AUS) | 27 | Delta Air Lines, Southwest Airlines Co., Top Air (Turkey) | — |
| John Glenn Columbus International Airport (CMH) | 26 | American Airlines, Delta Air Lines, Envoy Air Inc. | — |
| Phoenix Sky Harbor International Airport (PHX) | 26 | American Airlines, Top Air (Turkey), Delta Air Lines | — |
| Pittsburgh International Airport (PIT) | 26 | Top Air (Turkey), Delta Air Lines | — |
| Buffalo Niagara International Airport (BUF) | 25 | Top Air (Turkey), American Airlines | — |
| Tampa International Airport (TPA) | 25 | Top Air (Turkey), Delta Air Lines | — |
| Charles de Gaulle International Airport (CDG) | 24 | Air France, Top Air (Turkey), Delta Air Lines | — |
| Fort Lauderdale Hollywood International Airport (FLL) | 24 | Top Air (Turkey), Delta Air Lines | — |
| Seattle–Tacoma International Airport (SEA) | 24 | Alaska Airlines, Delta Air Lines | — |
| Southwest Florida International Airport (RSW) | 23 | Top Air (Turkey), Delta Air Lines | — |
| Amsterdam Airport Schiphol (AMS) | 22 | Delta Air Lines, Top Air (Turkey), KLM | — |
| Jacksonville International Airport (JAX) | 21 | Top Air (Turkey), Delta Air Lines | — |
| Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field (MSP) | 21 | Delta Air Lines, MN Airlines LLC | — |
| Toronto Pearson International Airport (YYZ) | 21 | Air Canada, Palau Micronesia Air | — |
| Adolfo Suárez Madrid–Barajas Airport (MAD) | 20 | Iberia, Top Air (Turkey), Delta Air Lines | — |
| Palm Beach International Airport (PBI) | 20 | Top Air (Turkey), Delta Air Lines | — |
| San Diego International Airport (SAN) | 20 | Alaska Airlines, Top Air (Turkey), Delta Air Lines, Southwest Airlines Co. | — |
| Cleveland Hopkins International Airport (CLE) | 19 | Delta Air Lines, Top Air (Turkey) | — |
| Richmond International Airport (RIC) | 19 | Delta Air Lines, Top Air (Turkey) | — |
| Charleston International Airport (CHS) | 18 | Top Air (Turkey), Delta Air Lines | — |
| George Bush Intercontinental Airport (IAH) | 18 | Albatross Airlines | — |
| Lisbon Humberto Delgado Airport (LIS) | 18 | TAP Portugal, Delta Air Lines | — |
| St. Louis Lambert International Airport (STL) | 18 | Southwest Airlines Co., Envoy Air Inc., American Airlines | — |
| Harry Reid International Airport (LAS) | 17 | Top Air (Turkey), Delta Air Lines | — |
| Savannah Hilton Head International Airport (SAV) | 16 | Top Air (Turkey), Delta Air Lines | — |
| Chicago Midway International Airport (MDW) | 15 | Southwest Airlines Co. | — |
| Luis Munoz Marin International Airport (SJU) | 15 | Top Air (Turkey) | — |
| Washington Dulles International Airport (IAD) | 13 | Albatross Airlines | — |
| Massena International Airport Richards Field (MSS) | 13 | Boutique Air, Inc. | — |
| Hancock County-Bar Harbor Airport (BHB) | 12 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Rome–Fiumicino Leonardo da Vinci International Airport (FCO) | 12 | ITA Airways, Delta Air Lines | — |
| Keflavik International Airport (KEF) | 12 | Icelandair | — |
| General Mitchell International Airport (MKE) | 12 | Top Air (Turkey), Delta Air Lines | — |
| Frederick Douglass Greater Rochester International Airport (ROC) | 12 | American Airlines | — |
| Syracuse Hancock International Airport (SYR) | 12 | American Airlines, Top Air (Turkey) | — |
| Lebanon Municipal Airport (LEB) | 11 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Martha's Vineyard Airport (MVY) | 11 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Zürich Airport (ZRH) | 11 | SWISS | — |
| Frankfurt Main Airport (FRA) | 10 | Lufthansa Cargo, Condor | — |
| Las Américas International Airport (SDQ) | 10 | Top Air (Turkey), Asian Air Company Limited | — |
| Augusta State Airport (AUG) | 9 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Long Island MacArthur Airport (ISP) | 9 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Frederick W. Smith International Airport (MEM) | 9 | Delta Air Lines, Four Island Air | — |
| Rutland - Southern Vermont Regional Airport (RUT) | 9 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Montreal / Pierre Elliott Trudeau International Airport (YUL) | 9 | Air Canada | — |
| Josep Tarradellas Barcelona-El Prat Airport (BCN) | 8 | Top Air (Turkey), Delta Air Lines | — |
| Dallas Love Field (DAL) | 8 | Southwest Airlines Co. | — |
| Edinburgh Airport (EDI) | 8 | Top Air (Turkey), Delta Air Lines | — |
| Knox County Regional Airport (RKD) | 8 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Daytona Beach International Airport (DAB) | 7 | Top Air (Turkey) | — |
| Cape Cod Gateway Airport (HYA) | 7 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Incheon International Airport (ICN) | 7 | Korean Air | — |
| Kansas City International Airport (MCI) | 7 | Delta Air Lines, Southwest Airlines Co. | — |
| Narita International Airport (NRT) | 7 | Japan Airlines | — |
| Athens Eleftherios Venizelos International Airport (ATH) | 6 | Delta Air Lines | — |
| Copenhagen Kastrup Airport (CPH) | 6 | SAS | — |
| Wilmington International Airport (ILM) | 6 | Top Air (Turkey), American Airlines | — |
| İstanbul Airport (IST) | 6 | THY - Turkish Airlines | — |
| Munich Airport (MUC) | 6 | Lufthansa Cargo | — |
| Presque Isle International Airport (PQI) | 6 | Top Air (Turkey) | — |
| Louisville Muhammad Ali International Airport (SDF) | 6 | UPS Airlines, Envoy Air Inc. | — |
| Salt Lake City International Airport (SLC) | 6 | Delta Air Lines | — |
| Shannon Airport (SNN) | 6 | Aer Lingus | — |
| Sarasota Bradenton International Airport (SRQ) | 6 | Top Air (Turkey) | — |
| Halifax / Stanfield International Airport (YHZ) | 6 | Panair do Brasil | — |
| Harrisburg International Airport (MDT) | 5 | American Airlines | — |
| Portland International Airport (PDX) | 5 | Alaska Airlines | — |
| Punta Cana International Airport (PUJ) | 5 | Top Air (Turkey) | — |
| El Salvador International Airport Saint Óscar Arnulfo Romero y Galdámez (SAL) | 5 | AVIANCA | — |
| Adirondack Regional Airport (SLK) | 5 | Hyannis Air Service, Inc. d/b/a Cap | — |
| Cibao International Airport (STI) | 5 | Top Air (Turkey) | — |
| Destin-Fort Walton Beach Airport (VPS) | 5 | Top Air (Turkey) | — |
| Calgary International Airport (YYC) | 5 | African International Airways | — |
| Zayed International Airport (AUH) | 4 | Etihad Airways | — |
| Dubai International Airport (DXB) | 4 | Emirates | — |
| Louis Armstrong New Orleans International Airport (MSY) | 4 | Top Air (Turkey) | — |
| Tocumen International Airport (PTY) | 4 | COPA Airlines | — |
| Brussels Airport (BRU) | 3 | Hainan Airlines | — |
| Francisco de Sá Carneiro Airport (OPO) | 3 | TAP Portugal | — |
| Norfolk International Airport (ORF) | 3 | Top Air (Turkey) | — |
| João Paulo II Airport (PDL) | 3 | SATA Internacional | — |
| Ben Gurion International Airport (TLV) | 3 | EL AL | — |
| London Gatwick Airport (LGW) | 2 | Top Air (Turkey) | — |
| Milan Malpensa International Airport (MXP) | 2 | Top Air (Turkey) | — |
| Cherry Capital Airport (TVC) | 2 | Delta Air Lines | — |
| Vienna International Airport (VIE) | 2 | Austrian | — |
GET /routes returns each scheduled flight from BOS: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
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