45 destinations have scheduled flights from SAT, about 831 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| Phoenix (PHX) | 78 | Southwest Airlines Co., American Airlines, Frontier Airlines, Inc., UPS Airlines | — |
| Dallas/Fort Worth International (DFW) | 67 | American Airlines, Envoy Air Inc., UPS Airlines, Federal Express | — |
| George Bush Intercontinental (IAH) | 65 | United Airlines, UPS Airlines, ABX Air, Inc., Mesa Airlines, Inc. | — |
| Love Field (DAL) | 62 | Southwest Airlines Co. | — |
| Denver International (DEN) | 56 | Southwest Airlines Co., United Airlines, Frontier Airlines, Inc. | — |
| Las Vegas (LAS) | 45 | Southwest Airlines Co., Frontier Airlines, Inc. | — |
| Chicago O'hare International (ORD) | 44 | Envoy Air Inc., United Airlines, American Airlines | — |
| Hartsfield-jackson Atlanta International (ATL) | 39 | Delta Air Lines, Southwest Airlines Co., Frontier Airlines, Inc. | — |
| Los Angeles International (LAX) | 38 | Delta Air Lines, SkyWest Airlines, Southwest Airlines Co. | — |
| William P Hobby (HOU) | 33 | Southwest Airlines Co., LLC "NORD WIND" | — |
| Internacional Benito Juarez (MEX) | 21 | Aeromexico, Viva Airlines, Volaris | — |
| Nashville International (BNA) | 20 | Southwest Airlines Co. | — |
| Orlando International (MCO) | 19 | Southwest Airlines Co., Spirit Airlines, Frontier Airlines, Inc. | — |
| Charlotte Douglas (CLT) | 18 | American Airlines | — |
| El Paso International Airport (ELP) | 16 | Southwest Airlines Co. | — |
| Midway (MDW) | 16 | Southwest Airlines Co. | — |
| Salt Lake City International (SLC) | 14 | Delta Air Lines | — |
| Detroit Metropolitan Wayne County (DTW) | 12 | Delta Air Lines | — |
| Monterrey (MTY) | 12 | Viva Airlines | — |
| Minneapolis - St. Paul International (MSP) | 11 | Delta Air Lines | — |
| Tampa International (TPA) | 11 | Southwest Airlines Co. | — |
| Louisville International (Standiford Field) (SDF) | 10 | UPS Airlines, Amerijet International Inc. | — |
| Lambert-St. Louis International (STL) | 10 | Southwest Airlines Co. | — |
| Baltimore/Washington International Thurgood Marshall (BWI) | 9 | Southwest Airlines Co. | — |
| San Diego (SAN) | 9 | Southwest Airlines Co. | — |
| Kansas City International Airport (MCI) | 8 | Southwest Airlines Co. | — |
| Logan International (BOS) | 7 | Delta Air Lines | — |
| Don Miguel Hidalgo y Costilla International (GDL) | 7 | Volaris | — |
| John F Kennedy International (JFK) | 7 | Delta Air Lines | — |
| Seattle-Tacoma International (SEA) | 7 | Alaska Airlines | — |
| Washington Dulles International (IAD) | 6 | United Airlines | — |
| Louis Armstrong New Orléans International Airport (MSY) | 6 | Southwest Airlines Co. | — |
| San Francisco International (SFO) | 6 | United Airlines | — |
| Memphis (MEM) | 5 | Federal Express | — |
| Miami International Airport (MIA) | 5 | American Airlines | — |
| Fort Worth Alliance (AFW) | 4 | Federal Express | — |
| Newark Liberty International (EWR) | 4 | United Airlines | — |
| Mc Allen Miller International (MFE) | 4 | Nextres AB, Daghestan Airlines | — |
| Greater Rockford Airport (RFD) | 4 | UPS Airlines | — |
| Francisco J. Múgica Internacional (MLM) | 3 | Volaris | — |
| Aeropuerto del Norte International Airport (NTR) | 3 | Nextres AB | — |
| Ingeniero Fernando Espinoza Gutiérrez International (QRO) | 3 | Viva Airlines | — |
| San Luis Potosí (SLP) | 3 | Volaris | — |
| Del Bajío International (BJX) | 2 | Viva Airlines | — |
| Industrial (ROW) | 2 | Viva Airlines | — |
GET /routes returns each scheduled flight from SAT: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
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